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Lower urinary tract symptoms and depression
Author(s) -
Rom Maximilian,
Schatzl Georg,
Swietek Natalia,
Rücklinger Ernst,
Kratzik Christian
Publication year - 2012
Publication title -
bju international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.773
H-Index - 148
eISSN - 1464-410X
pISSN - 1464-4096
DOI - 10.1111/j.1464-410x.2012.11552.x
Subject(s) - lower urinary tract symptoms , depression (economics) , medicine , international prostate symptom score , beck depression inventory , confidence interval , odds ratio , logistic regression , cohort , urinary system , prostate , psychiatry , anxiety , cancer , economics , macroeconomics
Study Type – Symptom prevalence (cohort) Level of Evidence 2b What's known on the subject? and What does the study add? Depression plays an important role in pathogenesis of BPH. Our study shows that prostatic symptoms can be helpful in the screening for depression. OBJECTIVE• To evaluate the relationship between lower urinary tract symptoms (LUTS) and depression in men through validated questionnaires.PATIENTS AND METHODS• Healthy male workers ( n = 673) were invited to a free health check‐up. • Patients underwent a detailed medical examination. • All participants completed the International Prostate Symptom Score (IPSS) questionnaire and the Beck Depression Inventory (BDI).RESULTS• Under multiple logistic regression analysis (adjusted for total testosterone and age), a significant effect of IPSS on BDI score was observed: mild depression (BDI score >9): odds ratio (OR) 1.092, 95% confidence interval (CI) 1.056–1.129; P < 0.001; moderate‐to‐severe depression (BDI score >19): OR 1.093, 95% CI 1.031–1.159; P = 0.003; and severe depression (BDI score >29): OR 1.176, 95% CI 1.048–1.320; P = 0.006.CONCLUSIONS• In healthy men, LUTS are significantly associated with depression. • The treatment of LUTS is very important for the mental health of older men.