Premium
Improving the prognosis of patients after radical cystectomy. Part II: the role of perioperative chemotherapy
Author(s) -
Suttmann Henrik,
Kamradt Jörn,
Lehmann Jan,
Stöckle Michael
Publication year - 2007
Publication title -
bju international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.773
H-Index - 148
eISSN - 1464-410X
pISSN - 1464-4096
DOI - 10.1111/j.1464-410x.2007.07113.x
Subject(s) - cystectomy , perioperative , chemotherapy , medicine , adjuvant chemotherapy , transitional cell carcinoma , general surgery , adjuvant , neoadjuvant therapy , clinical trial , intensive care medicine , oncology , bladder cancer , surgery , cancer , breast cancer
In this review we analyse the current status of perioperative systemic chemotherapy in the treatment of transitional cell carcinoma (TCC) of the bladder; instead of summarizing each neoadjuvant or adjuvant clinical trial we focus on the advantages and disadvantages of both strategies on the basis of theoretical considerations, and outline a rationale for a better design of future studies to confirm the efficacy of perioperative chemotherapy in TCC.