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Controversies regarding screening for prostate cancer
Author(s) -
Crawford E. David,
Thompson Ian M.
Publication year - 2007
Publication title -
bju international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.773
H-Index - 148
eISSN - 1464-410X
pISSN - 1464-4096
DOI - 10.1111/j.1464-410x.2007.06943.x
Subject(s) - health science , library science , citation , medicine , gerontology , medical education , computer science
Unfortunately, the specificity of the PSA test is not as good as its sensitivity. Although PSA is not a perfect test, high PSA levels should be viewed as a risk factor, much like cholesterol in cardiovascular disease. There is no specific upper threshold of cholesterol level at which a risk of cardiovascular disease appears; rather, the relation appears to be linear. The same can be said of PSA; PSA has a higher PPV than a DRE, at 30–42% vs 4–11% [7].