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CASE NUMBER AND THE FINANCIAL IMPACT OF CIRCUMCISION IN REDUCING PROSTATE CANCER
Author(s) -
Morris Brian J.,
Waskett Jake,
Bailis Stefan A.
Publication year - 2007
Publication title -
bju international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.773
H-Index - 148
eISSN - 1464-410X
pISSN - 1464-4096
DOI - 10.1111/j.1464-410x.2007.06875.x
Subject(s) - medicine , library science , gerontology , computer science
Prostate cancer risk is influenced by genetic and other factors, such as a diet high in red meat (1.3-fold increase in risk). As highlighted in various publications, including the BJU International recently [1], the risk also correlates with a history sexually transmitted infections (STIs), most consistently gonorrhoea, but also syphilis, human papillomavirus, and the recently discovered Molony murine leukaemia virus homologue XMRV. Such infections might establish in the prostate a state of chronic active inflammation, which is associated with various cancers. STIs are more common in uncircumcised men, three times more in a recent longitudinal study in New Zealand [2], which could explain why uncircumcised men have been reported to have 1.6–2.0 times the incidence of prostate cancer [3–6].