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A review of targeted screening for prostate cancer: introducing the IMPACT Study
Author(s) -
Mitra Anita V.,
Bancroft Elizabeth K.,
Eeles Rosalind A.
Publication year - 2007
Publication title -
bju international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.773
H-Index - 148
eISSN - 1464-410X
pISSN - 1464-4096
DOI - 10.1111/j.1464-410x.2007.06759.x
Subject(s) - prostate cancer , cancer , medicine , prostate , oncology
The scope of this review does not cover those men with Afro-Caribbean ancestry; it focuses instead on studies primarily of men with a positive family history. We aim to give a brief overview of current screening practices and highlight the genetic evidence for prostate cancer. A review of targeted screening practices leads to an introduction of our study, the Identification of Men with a genetic predisposition to ProstAte Cancer: Targeted screening for BRCA1 and BRCA2 carriers and controls ; the IMPACT study. This is the first international study to target PSA screening based upon known genotype.