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Prostate cancer detection in men with an initial diagnosis of atypical small acinar proliferation
Author(s) -
Mancuso Pascal A.,
Chabert Charles,
Chin Peter,
Kovac Paul,
Skyring Timothy,
Watt William H.,
Napaki Sabar
Publication year - 2007
Publication title -
bju international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.773
H-Index - 148
eISSN - 1464-410X
pISSN - 1464-4096
DOI - 10.1111/j.1464-410x.2007.06544.x
Subject(s) - medicine , biopsy , adenocarcinoma , prostate , prostate cancer , incidence (geometry) , prostatic adenocarcinoma , medical diagnosis , cancer , prostate biopsy , radiology , urology , pathology , physics , optics
OBJECTIVE To determine the subsequent prostatic adenocarcinoma detection rate amongst men with an initial diagnosis of atypical small acinar proliferation (ASAP). PATIENTS AND METHODS We reviewed the Illawarra Prostate Pathology Database over a 10‐year period (January 1994 to January 2004) for specimens diagnosed as ASAP. These specimens were re‐reviewed and clinical data obtained. RESULTS Of 61 cases of ASAP, there were complete follow‐up data for 31. In this group nine patients had no further biopsies at our institution; the other 22 had at least one repeat biopsy. The incidence of prostatic adenocarcinoma in this group was 17/31 (55%). This included 13 diagnoses on second biopsy, three on third biopsy and one diagnosed at another institution. CONCLUSION This study showed a detection rate for prostatic adenocarcinoma of 55% after an initial diagnosis of ASAP, which indicates that an initial diagnosis of ASAP mandates re‐biopsy.