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Survival analysis in patients with upper urinary tract transitional cell carcinoma: a comparison between open and hand‐assisted laparoscopic nephroureterectomy
Author(s) -
Hsueh Thomas Y.,
Huang YiHsiu,
Chiu Allen W.,
Huan Steven K.,
Lee YingHuei
Publication year - 2007
Publication title -
bju international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.773
H-Index - 148
eISSN - 1464-410X
pISSN - 1464-4096
DOI - 10.1111/j.1464-410x.2006.06665.x
Subject(s) - medicine , upper urinary tract , transitional cell carcinoma , cuff , urology , stage (stratigraphy) , surgery , urinary system , urinary bladder , bladder cancer , cancer , paleontology , biology
OBJECTIVE To evaluate the stage‐ and grade‐specific survival rate in patients with upper urinary tract (UUT) transitional cell carcinoma (TCC) after open (ONU) or hand‐assisted laparoscopic nephroureterectomy (LNU) with bladder‐cuff excision. PATIENTS AND METHODS From January 1998 to April 2005, 143 patients with UUT‐TCC were treated with either ONU or LNU and enrolled in the study. The peri‐operative data were collected by retrospective chart review. The recurrence, metastasis and survival rate were calculated. RESULTS The 5‐year disease‐specific survival of patients with pT1 disease was 88.1% after ONU and 92.0% after LNU ( P = 0.745); the respective values for patients with pT2 were 11/17 and 12/15 ( P = 0.874), and for pT3 were six/11 and 12/15 ( P = 0.476). The incidence of bladder recurrence within 2 years after surgery was 24.7% for ONU and 19.7% for LNU ( P = 0.475). CONCLUSION The results were similar after ONU or LNU with bladder‐cuff excision; bladder‐cuff excision using a hand‐assisted device is effective and serves as a treatment option for patients with UUT‐TCC.