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The impact of the overactive bladder on health‐related utility and quality of life
Author(s) -
CURRIE CRAIG J.,
MCEWAN PHIL,
POOLE CHRIS D.,
ODEYEMI ISAAC A.O.,
DATTA SHIBENDRA N.,
MORGAN CHRISTOPHER L.
Publication year - 2006
Publication title -
bju international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.773
H-Index - 148
eISSN - 1464-410X
pISSN - 1464-4096
DOI - 10.1111/j.1464-410x.2006.06141.x
Subject(s) - medicine , overactive bladder , quality of life (healthcare) , urinary incontinence , physical therapy , stress incontinence , body mass index , multivariate analysis , gerontology , urology , nursing , alternative medicine , pathology
OBJECTIVE To evaluate the impact of the overactive bladder (OAB) on quality of life and health‐related utility. PATIENTS AND METHODS In a study conducted in Cardiff and Vale NHS Trust, patients were identified from an academic urology unit inpatient database for admissions and sent a postal survey. The survey pack comprised questionnaires on demography, urological functioning, health utility (EQ5D index ), and health‐related quality of life (Short Form‐36, SF36). Respondents were classified according to general urinary status, frequency, urgency, and stress incontinence. RESULTS Of 2193 surveys dispatched, 609 (27.8%) were returned; of these patients, 52% had incontinence, of whom 83% had both frequency and urgency, and 60% stress incontinence. Patients with stress incontinence reported a mean ( sd ) EQ5D index of 0.578 (0.331), compared to 0.714 (0.281) for all other patients ( P < 0.001). From the SF36, respondents scored lowest in the role physical domain and highest in the mental domain, with mean scores of 33.8 and 72.1, respectively. Multivariate analysis of SF36 and EQ5D index scores, controlling for age, gender and body mass index, showed that incontinence was associated with a notable reduction in the EQ5D index and SF36 scores across all domains. CONCLUSION This study showed a significant reduction in quality of life for all patient groups with OAB; in particular, stress incontinence had the greatest impact.