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Photoselective vaporisation of the prostate randomised against turp‐preliminary results
Author(s) -
BOUCHIERHAYES D.M.,
ANDERSON P.A.,
VAN APPLEDORN S.,
BUGEJA P.,
COSTELLO. A.J.
Publication year - 2006
Publication title -
bju international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.773
H-Index - 148
eISSN - 1464-410X
pISSN - 1464-4096
DOI - 10.1111/j.1464-410x.2006.06085_92.x
Subject(s) - medicine , prostate , lower urinary tract symptoms , adverse effect , randomized controlled trial , urinary flow , urology , surgery , cancer
Many technologies have attempted to supplant TURP as the surgical treatment of choice in the treatment of lower urinary tract symptoms, but have not undergone randomised trials. Photoselective vaporization of the prostate (PVP) using the Greenlight ® laser system (Laserscope, San Jose, Ca.) gives an 80‐watt laser ablation system and here is compared to TURP in the world's first randomised trial. Study Design: One hundred and twenty patients are to be randomised to undergo TURP or PVP after evaluation which is repeated at 1, 3, 6 and 12 months. Irrigation use, length of catherisation time (LOC), length of hospital stay (LOS), blood loss and operative time are also assessed. All procedures were performed by fellows/registrars. Results: To date 90 patients are randomised and 68 are evaluable and were similar at baseline. Both techniques produced equivalent significant improvement in flow rates and IPSSs, and significantly shorter length of time of catherisation (LOC) and length of stay (LOS) in the PVP group. Adverse events were less frequent in the PVP group, and the procedure was 22% cheaper than TURP. Conclusions: This trial demonstrates with preliminary data that PVP may be an effective technique when compared to TURP, producing equivalent improvements in flow rates and IPSS scores with markedly reduced LOS, LOC and adverse events.