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Transurethral resection of prostate for locally advanced prostate cancer with bladder outlet obstruction
Author(s) -
BERJIDIS N.,
BOUCHIERHAYES D.M.,
THOMAS B.C.,
COSTELLO A.J.
Publication year - 2006
Publication title -
bju international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.773
H-Index - 148
eISSN - 1464-410X
pISSN - 1464-4096
DOI - 10.1111/j.1464-410x.2006.06085_90.x
Subject(s) - medicine , prostate cancer , urology , prostate , transurethral resection of the prostate , radiation therapy , cancer , surgery
Bladder outlet obstruction is a common complication of locally advanced carcinoma of the prostate. The aim of this study was to evaluate the operative morbidity and outcome after TURP for locally advanced prostate cancer and to compare it with the results from patients who had a TURP for benign prostate hyperplasia. Methods: Between January 1998 and December 2003 422 consecutive patients had a TURP for BPH and 53 consecutive patients underwent a TURP for LUTS with a diagnosis of locally advanced prostate cancer. Results: Mean age at time of surgery was 76.6 years (range 63–95) and mean PSA was 100.2 (range 0.3–2630) for those with cancer. Before the TURP 24.5% of the patients had hormonal treatment alone, 11.3% had radiotherapy and 64.2% had not treatment for their prostate cancer. At TURP histopathology revealed high grade cancer (Gleason score 8–10) in 75% and moderate grade (Gleason score 6 or 7) in 25%. Mean resection weight was 12.6 gram (range 2–65). There was no difference in the overall mortality, failure to void or complication rates between the established prostate cancer and the BPH group (Chi‐squared, P < 0.05). Conclusion: TURP can be performed with little fear of excess complications in patients with established cancer of the prostate gland.