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Hope springs eternal: cavernosal nerve regeneration
Author(s) -
SYME DAVID B.Y.,
CORCORAN NIALL M.,
BOUCHIERHAYES DAVID M.,
COSTELLO ANTHONY J.
Publication year - 2006
Publication title -
bju international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.773
H-Index - 148
eISSN - 1464-410X
pISSN - 1464-4096
DOI - 10.1111/j.1464-410x.2006.05767.x
Subject(s) - regeneration (biology) , prostate cancer , erectile dysfunction , medicine , prostatectomy , nerve injury , urology , anatomy , surgery , cancer , biology , microbiology and biotechnology
Erectile dysfunction after radical prostatectomy for prostate cancer remains a significant morbidity for a large group of patients. A large body of work suggests that disrupting the cavernosal nerves is central as a causative factor. Extensive research has focused on ways to increase potency rates after surgery, either by preserving neuro‐integrity, or attempting to restore it using various approaches. Herein we discuss the neurophysiology of nerve injury and regeneration, and review the work to date on cavernosal nerve regeneration.