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Bupivacaine provides rapid, effective periprostatic anaesthesia for transrectal prostate biopsy
Author(s) -
Rabets J.C.,
Jones J.S.,
Patel A.R.,
Zippe C.D.
Publication year - 2004
Publication title -
bju international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.773
H-Index - 148
eISSN - 1464-410X
pISSN - 1464-4096
DOI - 10.1111/j.1464-410x.2004.04843.x
Subject(s) - medicine , bupivacaine , lidocaine , anesthesia , visual analogue scale , biopsy , general anaesthesia , local anesthesia , prostate biopsy , surgery , local anaesthetic , transrectal ultrasonography , local anesthetic , prostate , radiology , cancer
OBJECTIVE To examine the effectiveness of the longer acting agent bupivacaine in providing periprostatic anaesthesia during transrectal ultrasonography (TRUS)‐guided biopsy, as the periprostatic injection of lidocaine has been shown to significantly alleviate the pain of this procedure. PATIENTS AND METHODS Seventy‐five patients were randomized to receive a periprostatic injection with either bupivacaine, a lidocaine/bupivacaine (1/1) combination, or no local anaesthesia. Immediately before biopsy 5 mL of the anaesthetic was injected under TRUS guidance into the periprostatic nerves bilaterally. After taking a 10‐core biopsy the patients were given a visual analogue scale (VAS; 0–10) to assess their pain during the procedure. RESULTS The mean VAS scores were 2.04 in the bupivacaine group and 4.46 in the control (no local anaesthetic) group ( P < 0.001). CONCLUSIONS Bupivicaine provides significant, immediate periprostatic anaesthesia for TRUS biopsy.