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The expression of ferritin on renal cancers and its relationship with cellular differentiation and tumour stage
Author(s) -
Yu D.S.,
Yueh K.C.,
Chang S.Y.,
Yang T.H.,
Ma C.P.
Publication year - 1995
Publication title -
british journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.773
H-Index - 148
eISSN - 1464-410X
pISSN - 0007-1331
DOI - 10.1111/j.1464-410x.1995.tb07381.x
Subject(s) - ferritin , renal cell carcinoma , stage (stratigraphy) , pathology , incidence (geometry) , population , immunohistochemistry , carcinoma , serum ferritin , cell , medicine , cancer research , biology , paleontology , physics , genetics , environmental health , optics
Objectives To investigate ferritin expression in renal carcinoma and the correlation of expression with tumour differentiation and stage. Patients and methods Ferritin was immunohistologically detected in 35 patients (23 men and 12 women; mean age 58.2 years, range 40‐82) with renal carcinoma and the findings compared with cellular type, tumour stage and the ferritin expression of a similar control population of 16 patients. Results The incidence of ferritin expression in renal carcinomas was 51%. Expression was significantly related to tumour stage and not cellular type. Conclusion The Results of this study re‐emphasize the high expression of ferritin in renal cell carcinoma and the correlation of expression with tumour behaviour.