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Results of radiotherapy on ureteric obstruction in muscle‐invasive bladder cancer
Author(s) -
Lichtenberg M. Honnens,
Miskowiak J.,
Rolff H.
Publication year - 1995
Publication title -
british journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.773
H-Index - 148
eISSN - 1464-410X
pISSN - 0007-1331
DOI - 10.1111/j.1464-410x.1995.tb07311.x
Subject(s) - medicine , bladder cancer , radiation therapy , percutaneous , surgery , catheter , urology , retrospective cohort study , ureter , cancer
Objective To evaluate the effect of radiotherapy on ureteric obstruction due to muscle‐invasive bladder cancer. Patients and methods Retrospective evaluation of the records of 5 74 patients with muscle‐invasive bladder cancer revealed 90 patients (16%) with ureteric obstruction; the obstruction was bilateral in 24%. The effect of radiotherapy was assessed in 55 patients with 68 obstructed kidneys. Six patients with eight obstructed kidneys required percutaneous nephros‐tomy or ureteric catheters in addition to radiotherapy. Results Drainage improved in 20% of kidneys and the diverting catheter was withdrawn permanently in one (17%) of the diverted patients. The median survival was 11 months. Irradiation was followed by significant complications in 37 patients (67%). Conclusion The results of this study raise doubts about the assumed beneficial effect of irradiation on ureteric obstruction due to muscle‐invasive bladder cancer. The short median survival of 11 months confirms that ureteric obstruction is a poor prognostic factor in muscle‐invasive bladder cancer.