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Ectopic human chorionic gonadotrophin (HCG) production: is the detection by serum analysis of HCG of clinical relevance in transitional cell carcinoma of the bladder?
Author(s) -
SMITH D. J.,
EVANS H. J.,
NEWMAN J.,
CHAPPLE C. R.
Publication year - 1994
Publication title -
british journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.773
H-Index - 148
eISSN - 1464-410X
pISSN - 0007-1331
DOI - 10.1111/j.1464-410x.1994.tb07605.x
Subject(s) - transitional cell carcinoma , clinical significance , medicine , human chorionic gonadotropin , grading (engineering) , cystoscopy , urology , gynecology , stage (stratigraphy) , ectopic pregnancy , oncology , hormone , urinary system , pregnancy , biology , bladder cancer , cancer , ecology , paleontology , genetics
Objective To assess the potential value of ectopic β‐human chorionic gonadotrophin (βHCG) measurement in the clinical management of transitional cell carcinoma (TCC). Patients and methods A prospective serological study of 16 3 consecutive patients undergoing cystoscopy as new or review cases was performed to assess any correlation between βHCG production and histological grading or stage. Results Ten per cent of patients with TCC had a raised βHCG level but there was no correlation with tumour differentiation, staging or prognosis. Conclusions βHCG has no role as a tumour marker for TCC and therefore appears unlikely to play a part in the clinical management or treatment of urothelial tumours.