Premium
Urinary calcium oxalate saturation in ‘stone formers' and normal subjects: an application of the EQUIL 2 program
Author(s) -
ROBERT M.,
BOULARAN A. M.,
COLETTE C.,
AVEROUS M.,
MONNIER M.
Publication year - 1994
Publication title -
british journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.773
H-Index - 148
eISSN - 1464-410X
pISSN - 0007-1331
DOI - 10.1111/j.1464-410x.1994.tb07596.x
Subject(s) - chemistry , calcium oxalate , calcium , oxalate , urinary system , saturation (graph theory) , uric acid , urine , ammonium oxalate , urinary calcium , potassium , medicine , endocrinology , inorganic chemistry , biochemistry , organic chemistry , mathematics , combinatorics
Objective To produce an index of lithogenic risk which identifies patients at risk of stone recurrence and facilitates the monitoring of prophylactic treatments. Patients and methods The EQUIL 2 , program provides an evaluation of the state of urinary saturation, particularly of calcium oxalate, based on the pH and total concentrations (mmol/l) of sodium, potassium, calcium, magnesium, uric acid, chloride, ammonium, citrate, phosphate, sulphate, oxalate, pyrophosphate and carbon dioxide. The morning urinary calcium oxalate saturation coefficient was thus calculated for 30 stone‐formers (Group 1) and 30 normal control subjects (Group 2). Results Urine from the majority of individuals was saturated, with no significant difference between the two groups. There appeared to be a correlation between the state of saturation and the urinary calcium oxalate molar product in both stone‐formers (r =0.931) and controls (r=0.914). Conclusion In future studies on urinary calcium oxalate saturation, it should be possible to supplement the sophisticated coefficient determined by the EQUIL, program with the molar product, except in cases where monitoring therapies have little or no effect on urinary oxalate or urinary calcium levels.