Premium
Serum level of immunosuppressive acidic protein in haemodialysis patients with or without renal cell carcinoma
Author(s) -
SASAGAWA I.,
NAKADA T.,
KUBOTA Y.,
SUZUKI H.,
SAWAMURA T.
Publication year - 1994
Publication title -
british journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.773
H-Index - 148
eISSN - 1464-410X
pISSN - 0007-1331
DOI - 10.1111/j.1464-410x.1994.tb07595.x
Subject(s) - renal cell carcinoma , medicine , creatinine , urology , carcinoma , hemodialysis , kidney , gastroenterology
Objective To assess the significance of immunosuppressive acidic protein (IAP) for detection of renal cell carcinoma in patients undergoing haemodialysis. Patients and methods The serum concentration of both IAP and creatinine was measured in 74 patients undergoing haemodialysis, 10 of whom had renal cell carcinoma and 64 of whom had no renal cell carcinoma. Control data was obtained from 13 healthy blood donors. Results The serum IAP level of patients undergoing haemodialysis was significantly elevated compared with that of the controls. The serum level of IAP inpatients with renal cell carcinoma who were undergoing haemodialysis was also considerably higher than that of patients with no renal cell carcinoma. The serum creatinine levels were not significantly different between patients with and without renal cell carcinoma but were significantly elevated when compared with the controls. Conclusion The measurement of serum IAP concentration is of value in the detection of renal cell carcinoma in patients undergoing haemodialysis.