Premium
Urethral Stricture following Transurethral Resection of the Prostate. The Role of Local Anaesthetics
Author(s) -
PANSADORO V.,
EMILIOZZI P.,
DEFIDIO L.,
SCARPONE P.,
TATI G.
Publication year - 1993
Publication title -
british journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.773
H-Index - 148
eISSN - 1464-410X
pISSN - 0007-1331
DOI - 10.1111/j.1464-410x.1993.tb16300.x
Subject(s) - medicine , tetracaine , transurethral resection of the prostate , urethral stricture , urethra , local anaesthetic , prostate , surgery , urology , lidocaine , cancer
Summary In a multicentre prospective study, 261 patients undergoing transurethral resection of the prostate (TURP) in 17 urology departments were randomised to receive lubricating jelly containing either 3% tetracaine hydrochloride, 1% lignocaine hydrochloride, or no local anaesthetic. No patient had a history of urethral instrumentation or a previous urethral stricture. After 6 months' follow‐up, 25/79 patients (32%) treated with 3% tetracaine jelly developed urethral strictures, as did 4/92 patients (4%) who received 1% lignocaine and 2/90 (2%) who received the jelly without anaesthetic. It was concluded that the use of 3% tetracaine jelly is associated with a high incidence of post‐TURP urethral strictures.