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Renal Transplantation in Young Boys with Posterior Urethral Valves: Preliminary Report
Author(s) -
DINNEEN M. D.,
FITZPATRICK M. M.,
GODLEY M. L.,
DICKSMIREAUX C. M. F.,
RANSLEY P. G.,
FERNANDO O. N.,
TROMPETER R. S.,
DUFFY P. G.
Publication year - 1993
Publication title -
british journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.773
H-Index - 148
eISSN - 1464-410X
pISSN - 0007-1331
DOI - 10.1111/j.1464-410x.1993.tb00733.x
Subject(s) - medicine , transplantation , surgery , urology , bilateral nephrectomy , nephrectomy , creatinine , renal function , bladder augmentation , urinary system , kidney , urinary bladder
Summary— Seven boys (mean age 38 months) with posterior urethral valves underwent renal transplantation between June 1988 and August 1991. Urodynamic studies were performed before transplantation in 6/7 patients. In 4 the investigation indicated bladders of capacity and compliance which were deemed suitable for transplantation. Two patients had poorly compliant bladders; one of these underwent bladder augmentation before engraftment and the other proceeded to transplantation without bladder surgery. Six patients have functioning renal allografts with a mean follow‐up of 1.3 years and a mean plasma creatinine of 51.6 μmol/l. Mean glomerular filtration rate (ml/min/1.73 m 2 SA) 6 months after transplantation was 76.8 and at 1 year it was 84.5. In one patient early rejection was followed by transplant nephrectomy. Careful pre‐operative evaluation is mandatory for a successful outcome of renal transplantation in young boys with posterior urethral valves.