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Prognostic Correlation of Morphometric Values with Survival in Invasive Transitional Cell Carcinoma of the Bladder
Author(s) -
PORTILLO J. A.,
VALBERNAL J. F.,
GARIJO M. F.,
BUELTA L.,
GUTIÉRREZ J. L.
Publication year - 1992
Publication title -
british journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.773
H-Index - 148
eISSN - 1464-410X
pISSN - 0007-1331
DOI - 10.1111/j.1464-410x.1992.tb15832.x
Subject(s) - pathology , papillary carcinoma , transitional cell carcinoma , carcinoma , medicine , biology , bladder cancer , cancer , thyroid , thyroid carcinoma
Summary A morphometric study was made of 95 invasive bladder tumours, differentiating 34 papillary and 61 solid carcinomas. In the invasive papillary tumours, the deeper the zone of the tumour measured, the higher the value of the mean nuclear area. A higher histological grade was also seen to correspond to a higher mean nuclear area value except for Grade IV tumours, whose nuclear area was no larger than that for Grade III tumours. This led us to separate Grade IV tumours from transitional cell carcinomas and classify them as undifferentiated. A better prognosis was found for those tumours whose mean nuclear area was ≤ 30 μm 2 in category T2. For T3 and T4A tumours no conclusive results were obtained in this respect.