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Germ Cell Alkaline Phosphatase in Human Seminal Plasma following Vasectomy
Author(s) -
LEWISJONES D. I.,
JOHNSON P. M.,
DESMOND A. D.,
McLAUGHLIN P. J.
Publication year - 1992
Publication title -
british journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.773
H-Index - 148
eISSN - 1464-410X
pISSN - 0007-1331
DOI - 10.1111/j.1464-410x.1992.tb15570.x
Subject(s) - alkaline phosphatase , vasectomy , germ cell , monoclonal antibody , andrology , chemistry , cell , enzyme , medicine , biology , endocrinology , antibody , biochemistry , immunology , population , research methodology , environmental health , family planning , gene
Summary— Germ cell alkaline phosphatase (also termed placental‐like alkaline phosphatase or Nagao isoenzyme) was assayed in seminal plasma using monoclonal antibody‐based enzyme immunoassays in samples obtained both before and after vasectomy. In all cases, germ cell alkaline phosphatase fell to undetectable levels within 14 days of operation. A fall in seminal plasma germ cell alkaline phosphatase may thus be an early indication of successful vasectomy.