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Neuro‐endocrine Cells—A New Prognostic Parameter in Prostate Cancer
Author(s) -
COHEN R. J.,
GLEZERSON G.,
HAFFEJEE Z.
Publication year - 1991
Publication title -
british journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.773
H-Index - 148
eISSN - 1464-410X
pISSN - 0007-1331
DOI - 10.1111/j.1464-410x.1991.tb15318.x
Subject(s) - endocrine system , grading (engineering) , prostate , occult , prostate cancer , medicine , incidence (geometry) , pathology , enteroendocrine cell , oncology , cancer , biology , hormone , ecology , physics , alternative medicine , optics
Summary Neuro‐endocrine cells are a recognised component of prostatic ducts and acini. Half of all clinically manifest cancers show neuro‐endocrine differentiation. Occult carcinomas have a lower incidence of such differentiation. Neuro‐endocrine cells are of major prognostic importance and appear more reliable in predicting patients' survival than do conventional histological grading systems.