Premium
Possible Relationship of Bladder Exstrophy and Epispadias with Progestins Taken during Early Pregnancy
Author(s) -
BLICKSTEIN I.,
KATZ Z.
Publication year - 1991
Publication title -
british journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.773
H-Index - 148
eISSN - 1464-410X
pISSN - 0007-1331
DOI - 10.1111/j.1464-410x.1991.tb15269.x
Subject(s) - epispadias , pregnancy , medicine , bladder exstrophy , early pregnancy factor , obstetrics , urology , surgery , gestation , biology , genetics
The effectiveness and safety of progesterone and its derivatives in the treatment of first‐trimester bleeding are still controversial. Of concern is the possible causal relationship between progestins and congenital anomalies. A cluster of infants with bladder exstrophy and epispadias born to women treated with progestins in early pregnancy is reported.