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Indoramin in the Treatment of Prostatic Bladder Outflow Obstruction
Author(s) -
STOTT M. A.,
ABRAMS P.
Publication year - 1991
Publication title -
british journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.773
H-Index - 148
eISSN - 1464-410X
pISSN - 0007-1331
DOI - 10.1111/j.1464-410x.1991.tb15194.x
Subject(s) - nocturia , medicine , placebo , residual urine , urology , residual volume , prostate , bladder outlet obstruction , surgery , urinary system , lung volumes , alternative medicine , pathology , cancer , lung
Summary— A series of 40 patients took part in a double‐blind, placebo‐controlled trial of indoramin in prostatic bladder outflow obstruction. Patients were assessed clinically and urodynamically before and after 4 weeks' treatment. Significant improvement was seen in nocturia, volume voided, flow rates and residual urine. The drug was well tolerated, although 7 patients on treatment and 7 on placebo noted side effects. These results suggest that indoramin may be a useful agent in the symptomatic management of bladder outflow obstruction.