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Urethral Blood Circulation during Cardiopulmonary Bypass
Author(s) -
TALJA M.,
LEHTOLA A.,
SALMENPERÄ M.,
RUUTU M.,
KARONEN S.L.,
ALFTHAN O.
Publication year - 1991
Publication title -
british journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.773
H-Index - 148
eISSN - 1464-410X
pISSN - 0007-1331
DOI - 10.1111/j.1464-410x.1991.tb15166.x
Subject(s) - extracorporeal circulation , medicine , cardiopulmonary bypass , perfusion , urethra , circulatory system , hemodynamics , blood flow , anesthesia , cardiology , surgery
Summary— The haemodynamic changes induced by extracorporeal circulation (ECC) are thought to be important in the induction of urethral strictures in open heart surgery when indwelling latex catheters are used. In the present study, 6 piglets were cannulated and connected to extracorporeal perfusion apparatus. Pump flows correlated with human ECC values with non‐haemic prime were used. The mucosal and submucosal blood circulation in the urethra reduced by 66% during ECC ( P <0.05). The brain and hepatic arterial flows increased. A significant reduction was seen in renal blood circulation. The changes in the urethral blood circulation during ECC correlated with previous findings. The reduced wash out levels of chemicals leaching from the indwelling latex catheters as a result of reduced local blood circulation are the main trigger for the induction of urethral strictures during ECC and in other shock‐like circulatory disturbances in the human body.