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Acute Changes in Kidney Function following Extracorporeal Shock Wave Lithotripsy for Renal Stones
Author(s) -
KARLSEN S. J.,
BERG K. J.
Publication year - 1991
Publication title -
british journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.773
H-Index - 148
eISSN - 1464-410X
pISSN - 0007-1331
DOI - 10.1111/j.1464-410x.1991.tb15126.x
Subject(s) - extracorporeal shock wave lithotripsy , renal function , urology , medicine , creatinine , urinary system , beta 2 microglobulin , albumin , excretion , urine , alkaline phosphatase , lithotripsy , endocrinology , surgery , chemistry , enzyme , biochemistry
Summary— Seventeen patients were subjected to analysis of various renal functional parameters before and after extracorporeal shock wave lithotripsy (ESWL) for renal stones. Thirteen patients were observed at 2 weeks and 3 months. Glomerular filtration rate (GFR) was not influenced by ESWL as based on unchanged serum levels of creatinine, β2‐microglobulin and creatinine clearance. A significant increase in urinary excretion of β‐microglobulin, N‐acetyl‐β‐glucosaminidase and alkaline phosphatase, with return to pre‐treatment values within 4 to 5 days, reflected transient disturbances in proximal tubular function. Urinary albumin excretion was increased 0–24 h after ESWL. No significant alterations were observed in plasma renin activity or serum aldosterone due to ESWL. Serum lactic dehydrogenase remained significantly increased for 2 weeks. In addition, significant changes in several blood and urine parameters were caused by immersion in water and intravenous infusions during treatment and were not specifically due to ESWL.