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Do Extracorporeal Shock Waves Affect Urinary Excretion of Glycosaminoglycans?
Author(s) -
KARLSEN S. J.,
SMEVIK B.,
LUND K. KLINGENBERG,
BERG K. J.
Publication year - 1991
Publication title -
british journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.773
H-Index - 148
eISSN - 1464-410X
pISSN - 0007-1331
DOI - 10.1111/j.1464-410x.1991.tb15062.x
Subject(s) - excretion , glycosaminoglycan , extracorporeal shock wave lithotripsy , urinary system , kidney , extracorporeal , medicine , shock (circulatory) , urology , endocrinology , lithotripsy , surgery , anatomy
Summary— Urinary excretion of glycosaminoglycans (GAGs) was studied in 9 anaesthetised dogs and 10 patients with single kidneys. The animals were studied for 4 to 5 hours after administration of shock waves to 1 kidney, the contralateral organ serving as control. Urinary excretion of GAGs was measured on both sides. The patients were studied 0 to 24 and 32 to 56 h after extracorporeal shock wave lithotripsy (ESWL). In the animals an increased mean urinary excretion of GAGs was observed on both sides; this was more marked in the treated kidney. The increase reflects tissue injury in the exposed kidney induced by the extracorporeal shock waves. No increase in mean urinary excretion of GAGs was observed in the patients.