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Double‐blind, Placebo‐controlled, Cross‐over Study of Flavoxate in the Treatment of Idiopathic Detrusor Instability
Author(s) -
CHAPPLE C. R.,
PARKHOUSE H.,
GARDENER C.,
MILROY E. J. G.
Publication year - 1990
Publication title -
british journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.773
H-Index - 148
eISSN - 1464-410X
pISSN - 0007-1331
DOI - 10.1111/j.1464-410x.1990.tb14994.x
Subject(s) - detrusor instability , placebo , medicine , pharmacotherapy , anesthesia , urology , pathology , alternative medicine , urinary incontinence
Summary— Detrusor instability occurs in approximately 10% of the adult population, producing troublesome symptoms. The pharmacotherapy currently available is usually only partially effective and cannot be adequately evaluated except under “blind” conditions because of the significant component attributable to placebo effects. The results of the present study revealed no advantage resulting from treatment with flavoxate, as assessed both subjectively and objectively. We suggest that this therapy does not appear to be beneficial in the medical management of detrusor instability.