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Does Microinvasion of the Capsule and/or Micrometastases in Regional Lymph Nodes Influence Disease‐free Survival after Radical Prostatectomy?
Author(s) -
HERING F.,
RIST M.,
ROTH J.,
MIHATSCH M.,
RUTISHAUSER G.
Publication year - 1990
Publication title -
british journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.773
H-Index - 148
eISSN - 1464-410X
pISSN - 0007-1331
DOI - 10.1111/j.1464-410x.1990.tb14899.x
Subject(s) - medicine , prostatectomy , lymph , capsule , radical retropubic prostatectomy , infiltration (hvac) , lymph node , metastasis , carcinoma , prostate , lymph node metastasis , radiation therapy , pathology , urology , radiology , cancer , botany , biology , thermodynamics , physics
Summary –Since 1976, 126 patients with clinically localised carcinoma of the prostate have been managed by radical retropubic prostatectomy. All patients with tumour spread beyond the capsule or metastasis in lymph nodes received radiotherapy. Tumour category pT3 was divided into invasion of the capsule or infiltration of the seminal vesicle. The disease‐free 10‐year survival rate in patients with minimal invasion of the capsule was 72% and in patients with infiltration of the seminal vesicles it was 26%. Unilateral lymph node metastases were classified as microscopic disease or macroscopic infiltration. The disease‐free 10‐year survival rate in patients with metastasis in 1 lymph node (micro‐ and macro‐metastasis) was 65% in contrast to 0% in patients with bilateral disease.