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Low Calcium Diet in Idiopathic Urolithiasis: A Risk Factor for Osteopenia as Great as in Primary Hyperparathyroidism
Author(s) -
FUSS M.,
PEPERSACK T.,
BERGMAN P.,
HURARD T.,
SIMON J.,
CORVILAIN J.
Publication year - 1990
Publication title -
british journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.773
H-Index - 148
eISSN - 1464-410X
pISSN - 0007-1331
DOI - 10.1111/j.1464-410x.1990.tb14819.x
Subject(s) - hypercalciuria , osteopenia , medicine , calcium , endocrinology , primary hyperparathyroidism , thiazide , hyperparathyroidism , bone mineral , secondary hyperparathyroidism , osteoporosis , parathyroid hormone , diuretic
Summary— The bone mineral content of the radius was measured in 32 male renal stone formers, 18 of them presenting with idiopathic urolithiasis and 14 with primary hyperparathyroidism, a disease known to disturb bone metabolism. The idiopathic stone formers had been on regular treatment with a low calcium diet. The bone mineral content of the radius was reduced to a similar level in both groups of patients. The data suggest that idiopathic stone formers on a low calcium diet are at risk of osteopenia; the factors which could lead to a negative calcium balance included uncompensated renal hypercalciuria, hypophosphataemia and exaggerated serum levels of 1,25‐dihydroxyvitamin D. To treat idiopathic hypercalciuria, thiazide diuretics, which reduce the renal excretion of calcium and have been shown to be beneficial for bone, seem safer than a low calcium diet.