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Treatment of Renal Colic by Prostaglandin Synthetase Inhibitors and Avafortan (Analgesic Antispasmodic)
Author(s) -
ELSHERIF A. E.,
FODA R.,
NORLEN L. J.,
YAHIA H.
Publication year - 1990
Publication title -
british journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.773
H-Index - 148
eISSN - 1464-410X
pISSN - 0007-1331
DOI - 10.1111/j.1464-410x.1990.tb07190.x
Subject(s) - antispasmodic , medicine , analgesic , renal colic , diclofenac , prostaglandin , anesthesia , intramuscular injection , pharmacology , alternative medicine , pathology
Summary— In a study of the pain‐relieving effect of 3 drugs commonly used to treat acute renal colic in this hospital, intravenous indomethacin and intramuscular diclofenac (prostaglandin synthetase inhibitors) were compared with intravenous Avafortan (analgesic antispasmodic). As first‐line analgesics, prostaglandin synthetase inhibitors, if given intravenously, offer an effective alternative to Avafortan. Of 145 patients studied, 32 required a second injection for complete relief of pain. Administering a second dose of prostaglandin synthetase inhibitors resulted in equally significant pain relief rate even though the route was intramuscular.