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Transurethral Resection of the Prostate and Bladder Tumour without Withdrawal of Warfarin Therapy
Author(s) -
PARR N. J.,
LOH C. S.,
Article A. D. DESMONDOriginal
Publication year - 1989
Publication title -
british journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.773
H-Index - 148
eISSN - 1464-410X
pISSN - 0007-1331
DOI - 10.1111/j.1464-410x.1989.tb05322.x
Subject(s) - medicine , warfarin , transurethral resection of the prostate , fresh frozen plasma , prostate , surgery , prothrombin time , resection , anesthesia , urology , atrial fibrillation , cancer , platelet
Summary— Twelve resections of prostate and 1 extensive bladder tumour were performed in patients on long‐term anticoagulation without withdrawal of warfarin therapy. The mean preoperative prothrombin index was 2.3. Four patients required blood transfusion. There were no major complications. The effects of surgery and infusion of fresh frozen plasma (FFP) on the level of anticoagulation were monitored. FFP reduced the prothrombin index by 0.25/unit. Transurethral resection can be carried out safely by an experienced urologist on patients anticoagulated with warfarin, reducing the risk of serious thromboembolic complications associated with withdrawal of anticoagulation.