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The Use of Endoscopic Detrusor Muscle Biopsies for in vitro Muscle Strip Studies
Author(s) -
HARRISON S. C. W.,
SIBLEY G. N. A.,
DOYLE P. T.,
FERGUSON D. R.
Publication year - 1988
Publication title -
british journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.773
H-Index - 148
eISSN - 1464-410X
pISSN - 0007-1331
DOI - 10.1111/j.1464-410x.1988.tb06380.x
Subject(s) - detrusor muscle , forceps , human muscle , muscle biopsy , in vitro , anatomy , smooth muscle , medicine , biopsy , urology , pathology , chemistry , surgery , skeletal muscle , biochemistry
Summary— A technique is described for performing in vitro muscle strip studies using samples of detrusor muscle taken by means of endoscopic biopsy forceps. This study of pig bladder muscle showed that the nerve mediated and drug induced responses of the muscle biopsies were similar to those produced by traditionally dissected muscle strips. The importance of continued access to human material for pharmacological studies is discussed.