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Seminal Analysis after Orchiectomy in Stage I Teratoma
Author(s) -
HORWICH A.,
NICHOLLS E. J.,
HENDRY W. F.
Publication year - 1988
Publication title -
british journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.773
H-Index - 148
eISSN - 1464-410X
pISSN - 0007-1331
DOI - 10.1111/j.1464-410x.1988.tb04272.x
Subject(s) - orchiectomy , azoospermia , medicine , sperm , stage (stratigraphy) , teratoma , testicular sperm extraction , urology , germ cell tumors , gynecology , andrology , surgery , infertility , pregnancy , biology , chemotherapy , paleontology , genetics
Summary— Seminal analysis was performed within 2 months of orchiectomy on 97 patients with clinical Stage I malignant testicular teratoma managed by surveillance following orchiectomy. Relapse of malignant disease occurred in 28% of 47 patients with a sperm count < 10 × 10 6 /ml and in 32% of 50 patients with a sperm count ≤ 10 × 10 6 /ml. Of 11 patients with azoospermia, 4 relapsed and 1 developed contralateral testicular germ cell tumour. Of 35 patients with malignant teratoma undifferentiated the relapse rate was 68% in 16 patients with a sperm count < 10 × 10 6 /ml and 42% in 19 patients with a sperm count ≤ 10 × 10 6 /ml. It was concluded that sperm count analysis is non‐contributory in estimating the risk of relapse in clinical Stage I teratoma.