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Improved Survival after Brain Metastases in Nonseminomatous Germ Cell Tumours with Combined Modality Treatment
Author(s) -
RAGHAVAN D.,
MACKINTOSH J. F.,
FOX R. M.,
ROGERS J.,
DUVAL P.,
BESSER M.
Publication year - 1987
Publication title -
british journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.773
H-Index - 148
eISSN - 1464-410X
pISSN - 0007-1331
DOI - 10.1111/j.1464-410x.1987.tb04987.x
Subject(s) - medicine , chemotherapy , cisplatin , germ cell , treatment modality , incidence (geometry) , oncology , germinoma , germ cell tumors , modality (human–computer interaction) , surgery , radiology , biology , biochemistry , physics , human–computer interaction , computer science , optics , gene
Summary— Long‐term disease‐free survival (78+ and 31+ months) has been achieved in two of four patients treated for brain metastases from non‐seminomatous germ cell tumours between 1980 and 1984. The incidence of cerebral metastases among 101 patients seen over the 5‐year period was 4%. The encouraging results from the use of combined modality treatment, incorporating cisplatin‐based chemotherapy, whole brain irradiation and surgery, are reviewed.