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Prospective Study of Intravesical Dimethyl Sulphoxide in the Treatment of Chronic Inflammatory Bladder Disease
Author(s) -
BARKER S. B.,
MATTHEWS P. N.,
PHILIP P. F.,
WILLIAMS GRANT
Publication year - 1987
Publication title -
british journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.773
H-Index - 148
eISSN - 1464-410X
pISSN - 0007-1331
DOI - 10.1111/j.1464-410x.1987.tb04805.x
Subject(s) - medicine , urology , prospective cohort study , surgery , biopsy
Summary— Thirty patients with biopsy‐proven chronic inflammatory bladder disease were treated with intravesical dimethyl sulphoxide (DMSO). Satisfactory symptomatic relief was achieved in 80% of patients completing treatment and no significant side effects were encountered. Despite the improvement in symptoms there was no significant alteration in the endoscopic or morphological appearance of the bladder after treatment. Intravesical DMSO is safe and relatively easy to administer and seems to have a place in the management of patients with this difficult problem.