Premium
Prevention of Xanthine Stone Formation by Augmented Dose of Allopurinol in the Lesch‐Nyhan Syndrome
Author(s) -
HIRAISHI K.,
NAKAMURA S.,
YAMAMOTO S.,
KUROKAWA K.
Publication year - 1987
Publication title -
british journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.773
H-Index - 148
eISSN - 1464-410X
pISSN - 0007-1331
DOI - 10.1111/j.1464-410x.1987.tb04654.x
Subject(s) - allopurinol , lesch–nyhan syndrome , xanthine , gout , medicine , xanthine oxidase , pharmacology , chemistry , hypoxanthine guanine phosphoribosyltransferase , biochemistry , enzyme , mutant , gene
Xanthine stone formation in patients with the Lesch‐Nyhan syndrome who are being treated with allopurinol may be prevented by increasing the dosage of the drug.