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Antibiotic Prophylaxis for Prostatic Surgery. Single‐dose Cephradine Compared with Single‐dose Cefotaxime
Author(s) -
BENTSI I. K.,
ELTON R. A.,
RITCHIE A. W. S.,
SMITH G.,
GOULD J. C.,
CHISHOLM G. D.,
HARGREAVE T. B.
Publication year - 1987
Publication title -
british journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.773
H-Index - 148
eISSN - 1464-410X
pISSN - 0007-1331
DOI - 10.1111/j.1464-410x.1987.tb04639.x
Subject(s) - cephradine , cefotaxime , medicine , antibiotic prophylaxis , antibiotics , significant difference , premedication , anesthesia , surgery , cephalosporin , microbiology and biotechnology , biology
Summary— Several previous studies have attested to the value of antibiotic prophylaxis for prostatic surgery. We report a prospective randomised study which compared a single dose of cefotaxime with a single dose of cephradine given with the induction of anaesthesia. There was little difference between these regimens and it was concluded that either may be used, depending on availability and cost of the antibiotic. We have now completed a 5‐year study of antibiotic prophylaxis for prostatic surgery and we also report the results of a long‐term survey of the ward flora. There has been no significant change and there is no evidence for the emergence of resistant strains.