Premium
Do Normal Mucosal Biopsies Predict Prognosis in Patients with Transitional Cell Carcinoma of Bladder Treated by Radical Radiotherapy?
Author(s) -
QUILTY P. M.,
HARGREAVE T. B.,
SMITH G.,
DUNCAN W.
Publication year - 1987
Publication title -
british journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.773
H-Index - 148
eISSN - 1464-410X
pISSN - 0007-1331
DOI - 10.1111/j.1464-410x.1987.tb04615.x
Subject(s) - medicine , carcinoma in situ , biopsy , radiation therapy , transitional cell carcinoma , carcinoma , dysplasia , urology , pathology , oncology , bladder cancer , cancer
Summary— A biopsy of normal‐looking mucosa showed mucosal abnormalities in 48.9% of patients with transitional cell carcinoma of the bladder. The presence of dysplasia or carcinoma in situ was significantly associated with grade but not with tumour category. In 100 patients who completed a course of radical megavoltage X‐ray therapy, the result of mucosal biopsy gave no significant prognostic information about tumour regression, durable local control, survival or the risk of subsequent metastases.