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Dose Titration in Clinical Trials
Author(s) -
MASSEY J. A.,
ABRAMS P.
Publication year - 1986
Publication title -
british journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.773
H-Index - 148
eISSN - 1464-410X
pISSN - 0007-1331
DOI - 10.1111/j.1464-410x.1986.tb09010.x
Subject(s) - anticholinergic , clinical trial , medicine , titration , urology , chemistry , inorganic chemistry
Summary— Seventy‐two women with proven detrusor instability completed a novel clinical trial of the new anticholinergic emepronium carrageenate (Cetiprin novum), which allowed for dose titration. The tolerated dose has been shown to correlate with the severity of symptoms. Statistically significant improvement was achieved in symptomatic and urodynamic parameters without serious side effects.