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True Hermaphroditism. A Review of 41 Cases with Observations on Testicular Histology and Function
Author(s) -
AARONSON I. A.
Publication year - 1985
Publication title -
british journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.773
H-Index - 148
eISSN - 1464-410X
pISSN - 0007-1331
DOI - 10.1111/j.1464-410x.1985.tb07052.x
Subject(s) - true hermaphroditism , testosterone (patch) , histology , basal (medicine) , biology , disorders of sex development , physiology , andrology , medicine , endocrinology , anatomy , karyotype , biochemistry , gene , insulin , chromosome
Summary— Thirty‐six children and five adults with true hermaphroditism have been reviewed. Twenty‐five were raised as males and 16 as females. Those assigned as males had all ovarian tissue excised, leaving either a single testis or the testicular portion of one or both ovotestes. Postoperative testicular function was studied in 15 males. Basal testosterone levels were low in all four post‐pubertal patients. Eleven children had plasma testosterone measured before and after stimulation with HCG. Response was poor in eight and normal in only three. Although social factors in South Africa usually result in true hermaphrodites being raised as males, the functional outcome of this decision is often disappointing