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Pelvic Lymphadenectomy and Radical Cystectomy for Transitional Cell Carcinoma of the Bladder with Pelvic Nodal Disease
Author(s) -
ZINCKE H.,
PATTERSON D. E.,
UTZ D. C.,
BENSON R. C.
Publication year - 1985
Publication title -
british journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.773
H-Index - 148
eISSN - 1464-410X
pISSN - 0007-1331
DOI - 10.1111/j.1464-410x.1985.tb06411.x
Subject(s) - cystectomy , medicine , lymphadenectomy , dissection (medical) , transitional cell carcinoma , stage (stratigraphy) , urology , bladder cancer , lymph node , urinary bladder , urinary diversion , surgery , cancer , biology , paleontology
Summary— Past and present methods of treatment for patients with stage D, (T1‐4 N+ M0) transitional cell cancer of the urinary bladder have proved to be largely ineffective. This report on 57 patients with stage D, disease confirms this impression and demonstrates that radical operation alone is associated with a 5‐year survival rate of only 10%. Survival is related to tumour grade and to the number of pelvic lymph nodes involved; furthermore, complete lymphadenectomy may contribute to improved patient survival. Effective treatment programmes for stage D 1 bladder cancer are lacking and efforts should be directed toward developing treatment protocols that combine radical cystectomy and meticulous pelvic node dissection with an effective adjuvant systemic treatment programme.