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The Management of Early Stage Non‐seminomatous Germ Cell Tumours of the Testis: Edinburgh 1970–1981
Author(s) -
DUNCAN W.,
MUNRO A. J.
Publication year - 1985
Publication title -
british journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.773
H-Index - 148
eISSN - 1464-410X
pISSN - 0007-1331
DOI - 10.1111/j.1464-410x.1985.tb05867.x
Subject(s) - medicine , orchiectomy , stage (stratigraphy) , radiation therapy , survival rate , disease , oncology , surgery , biology , paleontology
Summary— This study describes the management of early stage non‐seminomatous germ cell tumours of the testis in Edinburgh between 1970 and 1981. There were 69 patients in clinical Stage I and 22 patients in clinical Stage IIA. All were treated by orchiectomy and radiotherapy to the para‐aortic nodes. Some of the patients with Stage IIA disease received additional therapy. The overall 5‐year actuarial survival rate was 83%. In a group of 52 patients with Stage I disease who had had lymphography as part of their initial staging the 5‐year actuarial survival rate was 94.2%. The overall relapse rate was 27/91 (29.7%). The relapse rate in State IIA disease was 11/22 (50%) and the 5‐year actuarial survival rate was 64%. Patients with primary tumours beyond T1 had a significantly higher relapse rate than patients with T1 primary tumours: 10/20 (50%) and 13/52 (25%) respectively. The histology of the primary tumour did not have a statistically significant influence upon relapse rate.