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Does Calcium Contribute to the Effectiveness of a Coagulum for Pyelolithotomy?
Author(s) -
Watson G. M.,
Wickham J. E. A.,
Colvin B. T.
Publication year - 1984
Publication title -
british journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.773
H-Index - 148
eISSN - 1464-410X
pISSN - 0007-1331
DOI - 10.1111/j.1464-410x.1984.tb05348.x
Subject(s) - calcium , fibrinogen , urine , chemistry , surgery , medicine , biochemistry
Summary— Adding calcium to a mixture of thrombin and fibrinogen increased the breaking strain of the resultant coagulum by 10‐fold, but did not significantly reduce the length to which it could be stretched. There was no detectable change in the time taken for the coagulum to dissolve in urine. Simulation pyelolithotomies were performed on pig kidneys containing ball‐bearings which represented calculi. Coagula formed with calcium were significantly more effective at retrieving the ball‐bearings than coagula without calcium. It is concluded that the ideal coagulum formula should include 1 mmol of calcium.