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Urothelium and the Specific Red Cell Adherence Test
Author(s) -
GUNTER P. A.,
ABELABORG J. DE,
PUGH R. C. B.
Publication year - 1983
Publication title -
british journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.773
H-Index - 148
eISSN - 1464-410X
pISSN - 0007-1331
DOI - 10.1111/j.1464-410x.1983.tb07070.x
Subject(s) - urothelium , carcinoma in situ , squamous metaplasia , medicine , pathology , metaplasia , basal cell , urology , urinary bladder , carcinoma , epithelium
Summary— The Specific Red Cell Adherence Test (SRCAT) has been modified to produce clearer, more consistent, permanent preparations. Normal urothelium, inflammatory lesions, squamous metaplasia, papillomata, flat in situ and papillary tumours and invasive neoplasms of the bladder have been studied. Inflammatory and squamous changes did not corrupt the test results. The SRCAT was found to be a highly significant test for identifying those patients at risk from invasive bladder tumour. ABH antigens in carcinoma in situ appeared to be non‐uniformly distributed throughout the bladder urothelium; it is suggested that all subsequent biopsies from these patients should be tested.