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Experience with Beta‐HCG‐Positive Seminoma
Author(s) -
KUBER W.,
KRATZIK CH.,
SCHWARZ H. P.,
SUSANl M.,
SPONA J.
Publication year - 1983
Publication title -
british journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.773
H-Index - 148
eISSN - 1464-410X
pISSN - 0007-1331
DOI - 10.1111/j.1464-410x.1983.tb03369.x
Subject(s) - seminoma , immunoperoxidase , medicine , radiation therapy , chemotherapy , lymphadenectomy , stage (stratigraphy) , immunohistochemistry , pathology , gastroenterology , radiology , antibody , cancer , biology , immunology , paleontology , monoclonal antibody
Summary— The clinical findings, diagnosis and course of disease of eight patients with histological pure seminoma of the testis and positive serum P‐HCG levels are presented. In addition to routine investigations, immunohistochemical examination of the formalin‐fixed specimen by the immunoperoxidase technique was also carried out. Serum a feto‐protein levels of all eight patients remained normal. There was no correlation between serum P‐HCG level and tumour stage. The longest period of observation was 48 months, the shortest 11 months. All patients were treated primarily by radiotherapy. One patient also received chemotherapy and one patient underwent bilateral lymphadenectomy 13 months after radiotherapy.