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Urinary Incontinence in Old Age: A Controlled Clinical Trial of Emepronium Bromide
Author(s) -
WALTER S.,
HANSEN J.,
HANSEN L.,
MAEGAARD E.,
MEYHOFF H. H.,
NORDLING J.
Publication year - 1982
Publication title -
british journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.773
H-Index - 148
eISSN - 1464-410X
pISSN - 0007-1331
DOI - 10.1111/j.1464-410x.1982.tb06968.x
Subject(s) - anticholinergic , cystometry , urinary incontinence , medicine , placebo , urology , crossover study , anticholinergic agents , significant difference , urinary system , urinary bladder , anesthesia , alternative medicine , pathology
Summary— The effect of the anticholinergic agent, emepronium bromide (Cetiprin), was studied in a double blind crossover study of a group of elderly patients with urinary incontinence and uninhibited bladder contractions during cystometry. There was no statistically significant difference between the subjective effect of emepronium bromide and that of placebo, and no change in the cystometric parameters. The overall subjective cure or improvement rate was 79%. The effect of anticholinergic drugs in the treatment of urinary incontinence in elderly patients with uninhibited bladder contractions might to some extent be due to an improvement in the patients' understanding and acceptance of ihe bladder disorders.