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Hepatic Dysfunction in Renal Carcinoma
Author(s) -
FLETCHER M. S.,
PACKHAM D. A.,
PRYOR J. P.,
YATESBELL A. J.
Publication year - 1981
Publication title -
british journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.773
H-Index - 148
eISSN - 1464-410X
pISSN - 0007-1331
DOI - 10.1111/j.1464-410x.1981.tb03255.x
Subject(s) - medicine , nephrectomy , renal function , gastroenterology , liver function , liver function tests , carcinoma , retrospective cohort study , kidney
Summary— In a retrospective review of 81 patients with renal carcinoma 34 (42%) had abnormalities of one or more liver function tests. Fifteen patients (1 8.5%) had abnormalities of 3 or more liver function tests but without evidence of hepatic metastases. There was a significant association between these patients and the presence of fever, anemia, weight loss and a raised ESR ( P< 0.001) compared with those whose liver function was normal. Following nephrectomy, liver function returned to normal in 5 patients. Median survival in these patients was 35 months, whilst in those whose liver function remained abnormal the median survival was 8 months (P<0.01).