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Short‐term Antibiotic Prophylaxis and Prostatectomy *
Author(s) -
SHAH P. J. R.,
WILLIAMS GORDON,
CHAUDARY M.
Publication year - 1981
Publication title -
british journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.773
H-Index - 148
eISSN - 1464-410X
pISSN - 0007-1331
DOI - 10.1111/j.1464-410x.1981.tb03193.x
Subject(s) - incidence (geometry) , medicine , urinary system , antibiotic prophylaxis , antibiotics , prostatectomy , urology , urinary infection , surgery , prostate , physics , microbiology and biotechnology , cancer , optics , biology
Summary— Two hundred patients undergoing prostatic surgery at 2 hospitals were randomly allocated into 4 equal groups. The groups were a control, cephalexin, co‐trimoxazole and carfecillin treated groups. The incidence of urinary tract infections and other complications of prostatic surgery were studied in each group after a short‐term prophylactic regime of 3 doses of the antibiotic. The incidence of urinary infection was significantly improved from 28% in the control group to 8% and 1 6% in the co‐trimoxazole and cephalexin groups respectively. Carfecillin was not effective in reducing urinary infection. However, all 3 antibiotics reduced the incidence of other infective sequelae