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Single‐Drug Chemotherapy with 5‐FU and Adriamycin in Metastatic Bladder Carcinoma
Author(s) -
FOSSÅ SOPHIE D.,
GUDMUNDSEN T. E.
Publication year - 1981
Publication title -
british journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.773
H-Index - 148
eISSN - 1464-410X
pISSN - 0007-1331
DOI - 10.1111/j.1464-410x.1981.tb03188.x
Subject(s) - medicine , chemotherapy , doxorubicin , drug , fluorouracil , carcinoma , oncology , gastroenterology , pharmacology
Summary— Either 5‐fluorouracil (5‐FU) or Adriamycin was used as single‐drug treatment in 10 and 1 5 patients respectively with measurable metastatic bladder carcinoma. In the 5‐FU group there were one complete and 2 partial remissions. Six partial remissions were observed in patients treated with Adriamycin. The duration of the remissions was usually short. Gastrointestinal and haematological side effects were more pronounced in the Adriamycin group. The results are discussed in relation to other reports on cytostatic treatment of bladder carcinoma, with emphasis on general problems concerning chemotherapy of this disease.